Sha Liu, Professor

Research areas：Microneedles, Skin Organoids, Drug delivery

TeL：16602232742

Email：shaliu@tjut.edu.cn

Education & work experience

lChemical Engineering BS Zhejiang University

lChemical & Biological Engineering PhD SUNY-Buffalo,USA

lSenior Scientist KemLab（凯姆实验室）

lRun several start-ups, such as Haoxi Biotechnologies

Research Introduction

Dr.Liu’steam has achieved a closed loop from fundamental research to industrialization by integrating micro-/nanomaterials with biomedical engineering.Academically, the team has published multiple papers and patents on controlled fabrication and multi-scale characterization of micro-/nanomaterials.Industrially, using semiconductor processes, the team has developed silicon-based microneedle arrays, intradermal delivery systems, and automated injection tools, overcoming key challenges in microstructure transfer and patterning. Several products have obtained NMPA certification and entered global markets.

Using skin organoids, the team has developed physiologically relevant 3D models (including stratified epidermis, dermis, and hair follicles) for drug permeability testing, toxicity evaluation, and efficacy assessment, providing a human-relevant platform that bridges the gap between in vitro assays and clinical translation.The group is committed to advancing academic discoveries toward clinical and market applications, providing systematic solutions for real-world health challenges.

Selected Papers

（1）Sha Liu, Mark T. Swihart, Paras N. Prasad. Synthesis of Monodisperse Au, Ag and Au-Ag Alloy Nanoparticles with Tunable Size and Surface Plasmon Resonance Frequency. Chemistry of Materials, 2011, 23(18), 4098.

（2）Heong Sub Oh, Sha Liu, HongSub Jee, Alexander Baev, Mark T. Swihart, Paras N. Prasad.Chiral Poly(fluorene-alt-benzothiadiazole) (PFBT) and Nanocomposites with Gold Nanoparticles: Plasmonically and Structurally Enhanced Chirality. Journal of the American Chemical Society , 2010, 132(49), 17346.

（3）Sha Liu, Guangying Chen, Tymish Y. Ohulchanskyy, Mark T. Swihart, Paras N. Prasad.Facile Synthesis and Optical Characterization of Hybrid Upconverting and Plasmonic NaGdF4: Yb3+, Er3+/Silica/Gold Nanoparticles. Theranostics, 2013, 3(4), 275–281.

（4）Sha Liu, Hongwang Zhang, Mark T. Swihart. Spray Pyrolysis Synthesis of ZnS Nanoparticles from a Single-Source Precursor. Nanotechnology, 2009, 20, 235603.

（5）Guang S. He, Wing-Cheung Law, Alexander Baev, Sha Liu, Mark T. Swihart, Paras N. Prasad. Nonlinear Optical Absorption and Stimulated Mie Scattering in Metallic Nanoparticle Suspensions. Journal of Chemical Physics, 2013, 138(2), 024202.

（6）Guangying Chen, Tymish Y. Ohulchanskyy, Sha Liu, Wing-Cheung Law, Fang Wu, Mark T. Swihart, Hans Agren, Paras N. Prasad.Core/Shell NaGdF4:Nd3+/NaGdF4 Nanocrystals with Efficient Near-Infrared to Near-Infrared Downconversion Photoluminescence for Bioimaging Applications. ACS Nano, 2012, 6(4), 2969–2977.

（6）Munish Sharma, Parham Rohani, Sha Liu, Mark Kaus, Mark T. Swihart.Polymer and Surfactant-Templated Synthesis of Hollow and Porous ZnS Nano- and Micro-Spheres in a Spray Pyrolysis Reactor. Langmuir, 2015, 31(1), 413-423