Dr. Peng Zhang, Assistant Researcher
Email: zpeng@email.tjut.edu.cn
Address: Institute of Life and Health Intelligent Detection, Tianjin University of Technology, China
Education and Professional Experience
2022.01 – present: Tianjin University of Technology, Institute of Life and Health Intelligent Detection, Assistant Researcher
2017.09 – 2021.12: Nankai University, Ph.D. in Science (Supervisor: Prof. Yi Luo)
2014.09 – 2017.07: Hainan University, M.S. in Agriculture (Supervisor: Prof. Yanping Luo)
2010.09 – 2014.07: Hainan University, B.S. in Engineering
Dr. Zhang serves as a Youth Editorial Board Member for Food Science and Human Wellness and Journal of Future Foods. He also acts as a regular peer reviewer for several SCI-indexed journals, including Journal of Controlled Release, ACS Nano, BMC Microbiology, Food Science and Human Wellness, and Journal of Future Foods. He contributed to the development of an industry standard – Technical Specification for Earthworm Farming (Standard No. T/APEP 1034-2025). As a key contributor, he received the Third Prize of Tianjin Science and Technology Progress Award in 2025 for the project “Key Technologies for Precision Diagnosis and Treatment of Diabetes Combined with Infection”. He has delivered multiple academic presentations at the National Conference on Environmental Chemistry and the National Conference on Ecotoxicology.
Research Grants and Participation
1.National Natural Science Foundation of China (NSFC) – General Program: “Distribution and proliferation mechanisms of antibiotic resistance genes in the human gut microbiota” (participant)
2.NSFC – Young Scientists Fund: “Mechanisms of Helicobacter pylori eradication on the distribution of resistance genes and bacterial resistance evolution in the gut microbiota” (Principal Investigator, 300,000 RMB)
3.Open Fund of Key Laboratory: “Mechanisms of gut microbiota influencing Proteus urinary tract infection” (Principal Investigator, 50,000 RMB)
Research Directions
1.Mechanisms of ARG proliferation and bacterial resistance evolution in the intestinal microenvironment; combined omics and animal model studies on xenobiotics–gut microbiota interactions and associated health risks.
2.Synthesis of drugs targeting digestive system diseases; construction of efficient drug delivery systems based on bile acids, biopolysaccharides, liposomes, and PLGA.
Publications
1.Zhang, P., Zhao, M., Cheng, Z., Ding, Y., Xia, S., & Guo, J. Bile acid metabolism dysregulation following Helicobacter pylori eradication promotes plasmid-mediated antimicrobial resistance in the gut microbiome. The ISME Journal, wrag126. 2026, Advance online publication. https://doi.org/10.1093/ismejo/wrag126.
2.Zhao, M., Zhou, H., Jiang, R., Gao, Y.,Zhang, P., & Wang, F. Colon-targeted alginate/chitosan microspheres for co-delivery of synbiotics and nanozymes ameliorate inflammatory bowel disease. Food Research International, 2026, 239, 119533.
3.Liu, H., Han, B., Yao, H., Wang, J., Xv, F., Xv, Y., Zhang, M., Lin, M., Li, Z., Wang, S., Zhang, Y., Gao, J., Zhang, Y., &Zhang, P. Robot-assisted gait training alleviates the symptoms of acute ischemic stroke via regulating gut microbiota composition and function. Frontiers in Cellular and Infection Microbiology, 2026, 16, 1810501.
4.Li, S.,Zhang, P., Li, Y., Zhao, M., & Deng, H. Interface-Engineered Oral Hybrid Nanotherapeutics Combining Cerium Nanozymes and Extracellular Vesicles for Multimodal Regulation of Inflammatory Bowel Disease. ACS Applied Materials & Interfaces, 2026, 18(6), 10416–10427.
5.Zhao, M., Zhang, Y., Liu, S., Wang, F., &Zhang, P. Eradication of Helicobacter pylori reshapes gut microbiota and facilitates the evolution of antimicrobial resistance through gene transfer and genomic mutations in the gut. BMC Microbiology, 2025, 25(1), 90.
6.Zhang, P., Cheng, Z., Cao, Y., Liu, S., & Zhao, M. Genomic epidemiology of antimicrobial resistance in Proteus mirabilis: core genome and plasmid-mediated drivers. BMC Microbiology, 2025, 26(1), 89.
7. Zhao, M., Tang, F., Huang, X., Ma, J., Wang, F., &Zhang, P. Polysaccharide Isolated from Agaricus blazei Murill Alleviates Intestinal Ischemia/Reperfusion Injury through Regulating Gut Microbiota and Mitigating Inflammation in Mice.Journal of agricultural and food chemistry. 2024, 72(4), 2202–2213.
8.Liu, L., Lu, X., Li, S., &Zhang, P. Polysaccharides isolated from Hibiscus sabdariffa L. mitigate intestinal radiation injury through relieving mucosal inflammation and reshaping gut microbiota in mice. Journal of Functional Foods, 2024, 121.
9.Zhao, M., Ma, J., Liu, H., Luo, Y., Deng, H., Wang, D., Wang, F., &Zhang, P.The Gut Microbiota Contributes to Systemic Responses and Liver Injury in Gut-Derived Sepsis. Microorganisms, 2023, 11(7), 1741.
10.Gao, Y.,Zhang, P.,Wei, Y., Ye, C., Mao, D., Xia, D., & Luo, Y. Porphyromonas gingivalis exacerbates alcoholic liver disease by altering gut microbiota composition and host immune response in mice. Journal of Clinical Periodontology, 2023, 50(9), 1253–1263.
11.Zhang P., Zheng L., Duan Y., Gao Y., Gao H., Mao D., Luo Y.. Gut microbiota exaggerates triclosan-induced liver injury via gut-liver axis. J Hazard Mater, 2022, 421:126707.
12.Zhang P., Mao D., Gao H., Zheng L., Chen Z., Gao Y., Duan Y., Guo J., Luo Y., Ren H. Colonization of gut microbiota by plasmid-carrying bacteria is facilitated by evolutionary adaptation to antibiotic treatment. ISME J, 2021 Dec 13.
13.Meng, D.,Zhang, P., Li, S., Ho, C. T., Zhao, H. Antioxidant activity evaluation of dietary phytochemicals using Saccharomyces cerevisiae as a model. Journal of Functional Foods, 2017, 38: 36-44.
14.Meng, D.,Zhang, P.,Zhang, L., Wang, H., Ho, C. T., Li, S., Zhao, H. Detection of cellular redox reactions and antioxidant activity assays. Journal of Functional Foods, 2017, 37:467-479.
