Dr.Wei Zhang, Assistant Researcher

Address: Institute of Life and Health Testing, Tianjin University of Technology

Tel: 022-60215055

Email: wei_zhang@email.tjut.edu.cn

Education background：

2010/09-2014/06, Jilin University, Bachelor Degree

2014/08-2020/01, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Ph.D.

Research Interests:Establishing in vitro 2/3D cells culture platform

(1) Fabrication dynamic patterned stem cell fate control platform;

(2) Construction of 3D hydrogels mimic the tumor microenvironment and exploration of tumor genesis and development mechanism.

Projects:

1. National Natural Science Foundation of China，No. 22205161, Construction and application of 3D polymer hydrogels which can mimic the tumor microenvironment, 2023.01-2025.12, 30W, Leader.

2. National Natural Science Foundation of China,No. 51973214,Preparation of biomedical nanomaterials via multi-component reactions, 2020.01-2023.12, 59W, Participate in.

3. National Natural Science Foundation of China, No. 51773197, Anti-PD-1/PD-L1 antibody vesicles responsive to tumor microenvironment for cancer chemotherapy/immunotherapy, 2018.01-2021.12, 58W, Participate in.

Publications：

1. Lou X.; Wang H.; Liu Y.; Huang Y.; Liu Z.;Zhang, W.(通讯作者); Tie W.; Perylene-Based Reactive Oxygen Species Supergenerator for Immunogenic Photochemotherapy against Hypoxic Tumors,Angewandte Chemistry International Edition, 2023, 62, e202214586.IF:16.823

2. Zhang B., Zheng R., Liu Y., Lou X.,Zhang, W., Cui Z., Huang Y., Tie W., Perylene-Mediated Electron Leakage in Respiratory Chain to Trigger Endogenous ROS Burst for Hypoxic Cancer Chemo-Immunotherapy, Advanced Science, 2023, 10(3): 2204498. IF:17.521

3. Zhang, W., Lin, W.; Li, C.; Liu, S.; Hu, X.; Xie, Z., Rational Design of BODIPY-Diketopyrrolopyrrole Conjugated Polymers for Photothermal Tumor Ablation.ACS Applied Materials&Interfaces2019, 11, 32720-32728. IF:10.383

4. Zhang, W.; Lin, W.; Wang, X.; Li, C.; Liu, S.; Xie, Z., Hybrid Nanomaterials of Conjugated Polymers and Albumin for Precise Photothermal Therapy. ACS Applied Materials&Interfaces 2019, 11, 278-287. IF:10.383

5. Zhang, W.; Lin, W.; Zheng, X.; He, S.; Xie, Z., Comparing Effects of Redox Sensitivity of Organic Nanoparticles to Photodynamic Activity.Chemistry of Materials2017, 29, 1856-1863. IF:10.508

6. Zhang, W.; Lin, W.; Pei, Q.; Hu, X.; Xie, Z.; Jing, X., Redox-Hypersensitive Organic Nanoparticles for Selective Treatment of Cancer Cells. Chemistry of Materials 2016, 28, 4440-4446. IF:10.508

7. Zhang, W.; Xie, Z.; Jing, X., Diselenide organic molecules self-assembled nanomedicines for selective treatment of cancer cells.Journal of Controlled Release2017, 259, e135. IF:11.467

8. Zhang, W.; Xie, Z., Fabrication of palladium nanoparticles as effective catalysts by using supramolecular gels.Chinese Chemical Letters2016, 27, 77-80. IF:8.455

9. Zong, S.; Wang, X.; Lin, W.; Liu, S.;Zhang, W.^⁕, Simple D-A-D Structural Bisbithiophenyl Diketopyrrolopyrrole as Efficient Bioimaging and Photothermal Agents.Bioconjugate Chemistry2018, 29, 2619-2627. IF:6.069

10. Zhang, T.,Zhang, W.^⁕, Zheng, M., Xie, Z., Near-infrared BODIPY-paclitaxel conjugates assembling organic nanoparticles for chemotherapy and bioimaging.Journal of colloid and interface science2018, 514, 584-591. IF:9.965

11. Li, C., Lin, W., Liu, S.,Zhang, W.^⁕, Xie, Z., Self-destructive PEG-BODIPY nanomaterials for imaging and phototherapy.Journal of Materials Chemistry B, 2019, 7, 4655-4660. IF:7.571