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院长

王铁博士 教授 研究员 博士生导师

天津理工大学副校长

生命健康智能检测研究院院长

天津市生命健康检测重点实验室主任

研究方向:基于纳米自组装的生命流动体系分析检测

电子邮件:wangtie@email.tjut.edu.cn

通讯地址:天津市西青区宾水西道391号

 

荣誉和奖励:

2019年国家基金委杰出青年科学基金

2019年国家高层次人才特殊支持计划

2018年科技部中青年科技创新领军人才

2018年中国科学院创新交叉团队负责人

2014年国家基金委优秀青年科学基金(结题评优)

2013年国家海外高层次人才引进计划

2023年获纳米研究青年科学家奖(Young Innovator Award of Nano Research)

2021年获国际先进材料学会奖章(IAAM Medal)

2018年获中国分析测试协会科学技术奖一等奖(第一完成人)

学术兼职:

Rare Metals编委

Fundamental Research编委

Nano Research编委

Progress in Chemistry编委

高等学校化学学报编委

主要研究成果:

王铁研究员以纳米材料自组装结构为基础,长期致力于疾病体外分析检测的研究及应用,围绕疾病标志物检测的关键科学问题,开展了系统的原创性工作,并取得了一系列创新性成果和突出成绩。利用纳米组装力学性能-微纳结构调控-疾病体外检测的内在关系,构建适用于流动复杂体系的高灵敏度和高选择性的新型纳米组装结构,研究了纳米组装表界面结构与分析检测的构效关系,探索了自组装微纳结构和疾病化学信息的相互作用机制,发现流动形态对疾病标志物吸附动力学的影响机制,开发了适用于流动复杂体系检测的新方法、新材料和新技术平台;研制便携式肺癌呼出气检测仪器,突破实时在线的早期肺癌筛查快检技术,开展疾病早期检测临床试验;最终实现从基础研究、仪器研制到临床检测的全链条研究平台。在Science,J. Am. Chem. Soc.,Adv. Mater.,Angew. Chem.,Nat. Commun.,Sci. Adv.等核心杂志发表论文共110余篇,他引次5800余次。申请发明专利20项,已授权12项。

代表性论文著作:

1.Xue Lou, Hui Wang, Yu Liu, Yongwei Huang*, Zhonghua Liu, Wei Zhang*, Tie Wang*.Perylene-Based Reactive Oxygen Species Supergenerator for Immunogenic Photochemotherapy against Hypoxic Tumors.Angew. Chem. Int. Ed., 2023, DOI:10.1002/anie.202214586.

2.Xiangyu Chen, Shiyong Teng, Jinming Li, Xuezhi Qiao, Weidong Zhao, Zhengjie Xue, Xudong Shi*, Yuguang Wang*, Wensheng Yang*, Tie Wang*.Gadolinium(III)-Chelated Deformable Mesoporous Organosilica Nanoparticles as Magnetic Resonance Imaging Contrast Agent.Adv. Mater., 2023, 2211578.

3. Xiaobin Huang, Weidong Zhao, Xiangyu Chen, Jinming Li, Haochen Ye, Cancan Li, Xiaomeng Yin, Xinyuan Zhou, Xuezhi Qiao, Zhenjie Xue*, and Tie Wang*.Gold Nanoparticle-Bridge Array to Improve DNA Hybridization Efficiency of SERS Sensors.J.Am. Chem. Soc., 2022,144, 17533-17539.

4. Weidong Zhao, Jinming Li, Zhenjie Xue, Xuezhi Qiao, Ailin Li, Xiangyu Chen, Yun Feng,* Zhou Yang,* Tie Wang*.A Separation-Sensing Platform Performing Accurate Diagnosis of Jaundice in Complex Biological Tear Fluids.Angew. Chem. Int. Ed., 2022, 61, e202205628(1 of 6).

5.Xiao Li*, Zhenjie Xue, Xiangyu Chen, Xuezhi Qiao, Guang Mo, Wensheng Bu, Bo Guan, Tie Wang*.Printable Assemblies of Perovskite Nanocubes on Meter-Scale Panel.Sci. Adv., 2022, DOI: 10.1126/sciadv.add1559.

6. Chuanhui Huang, Xiangyu Chen, Zhenjie Xue, Tie Wang*, Nanoassembled interface for dynamics tailoring,Acc. Chem. Res. 2021, 54, 35-45.

7. Lu Liu, Wei Xiong, Linfeng Cui, Zhenjie Xue, Chuanghui Huang, Qian Song, Wanqiao Bai, Yage Peng, Xiangyu Chen, Keyan Liu, Shuwei Zhang, Lei Wen, Yanke Che,* and Tie Wang.* Universal Strategy for Improving the Sensitivity of Detecting Volatile Organic Compounds by Patterned Arrays.Angew. Chem. Int. Ed., 2020, 59, 15953-15957.

8. Qian Song, Zhenjie Xue, Cong Liu, Xuezhi Qiao, Lu Liu, Chuanhui Hunag, Keyan Liu, Xiao Li, Zhili Lu, and Tie Wang*,General strategy to optimize gas evolution reaction via assembled striped-pattern superlattices,J. Am. Chem. Soc., 2020, 142(4), 1857-1863.

9. Chuanhui Huang, Xiangyu Chen, Zhenjie Xue, Tie Wang*, Effect of structure: A new insight into nanoparticle assemblies from inanimate to animate.Sci. Adv., 2020, 6: eaba1321.

10. Chuanhui Huang, Zhihong Guo, Xu Zheng, Xiangyu Chen, Zhenjie Xue, Shuwei Zhang, Xiao Li, Bo Guan, Xiang Li, Guoqing Hu* and Tie Wang*. Deformable Metal–Organic Framework Nanosheets for Heterogeneous Catalytic Reactions.J. Am. Chem. Soc.,  2020, 142(20), 9408-9414.