张巍博士，助理研究员
通讯地址：天津理工大学生命健康检测研究院
电话：022-60215055
邮箱：wei_zhang@email.tjut.edu.cn
教育背景
2010/09-2014/06，吉林大学，学士
2014/08-2020/01，中国科学院长春应用化学研究所，博士
科研方向：建立体外2/3D细胞培养平台
具体方向：
1、开发动态图案化干细胞命运操控平台；
2、3D仿生肿瘤微环境平台的构建及肿瘤发生发展机制探索；
科研项目：
1、国家自然科学基金青年项目，可模拟肿瘤微环境的3D高分子水凝胶构建及应用研究，2023.01-2025.12，30万，主持。
2、国家自然科学基金委员会，面上项目，51973214，多组分反应制备生物医用纳米材料，2020-01-01至2023-12-31，59万元，在研，参与。
3、国家自然科学基金委员会，面上项目，51773197,肿瘤微环境响应的anti-PD-1/PD-L1抗体囊泡用于癌症化疗/免疫协同治疗，2018-01-01至2021-12-31，58万元，在研，参与。
论文著作：
1、Lou X.; Wang H.; Liu Y.; Huang Y.; Liu Z.;Zhang, W.(通讯作者); Tie W.; Perylene-Based Reactive Oxygen Species Supergenerator for Immunogenic Photochemotherapy against Hypoxic Tumors,Angewandte Chemistry International Edition, 2023, 62, e202214586.IF:16.823
2、Zhang B., Zheng R., Liu Y., Lou X.,Zhang, W., Cui Z., Huang Y., Tie W., Perylene-Mediated Electron Leakage in Respiratory Chain to Trigger Endogenous ROS Burst for Hypoxic Cancer Chemo-Immunotherapy, Advanced Science, 2023, 10(3): 2204498. IF:17.521
3、Zhang, W., Lin, W.; Li, C.; Liu, S.; Hu, X.; Xie, Z., Rational Design of BODIPY-Diketopyrrolopyrrole Conjugated Polymers for Photothermal Tumor Ablation.ACS Applied Materials&Interfaces2019, 11, 32720-32728. IF:10.383
4、Zhang, W.; Lin, W.; Wang, X.; Li, C.; Liu, S.; Xie, Z., Hybrid Nanomaterials of Conjugated Polymers and Albumin for Precise Photothermal Therapy. ACS Applied Materials&Interfaces 2019, 11, 278-287. IF:10.383
5、Zhang, W.; Lin, W.; Zheng, X.; He, S.; Xie, Z., Comparing Effects of Redox Sensitivity of Organic Nanoparticles to Photodynamic Activity.Chemistry of Materials2017, 29, 1856-1863. IF:10.508
6、Zhang, W.; Lin, W.; Pei, Q.; Hu, X.; Xie, Z.; Jing, X., Redox-Hypersensitive Organic Nanoparticles for Selective Treatment of Cancer Cells. Chemistry of Materials 2016, 28, 4440-4446. IF:10.508
7、Zhang, W.; Xie, Z.; Jing, X., Diselenide organic molecules self-assembled nanomedicines for selective treatment of cancer cells.Journal of Controlled Release2017, 259, e135. IF:11.467
8、Zhang, W.; Xie, Z., Fabrication of palladium nanoparticles as effective catalysts by using supramolecular gels.Chinese Chemical Letters2016, 27, 77-80. IF:8.455
9、Zong, S.; Wang, X.; Lin, W.; Liu, S.;Zhang, W.⁕, Simple D-A-D Structural Bisbithiophenyl Diketopyrrolopyrrole as Efficient Bioimaging and Photothermal Agents.Bioconjugate Chemistry2018, 29, 2619-2627. IF:6.069
10、Zhang, T.,Zhang, W.⁕, Zheng, M., Xie, Z., Near-infrared BODIPY-paclitaxel conjugates assembling organic nanoparticles for chemotherapy and bioimaging.Journal of colloid and interface science2018, 514, 584-591. IF:9.965
11、Li, C., Lin, W., Liu, S.,Zhang, W.⁕, Xie, Z., Self-destructive PEG-BODIPY nanomaterials for imaging and phototherapy.Journal of Materials Chemistry B2019, 7, 4655-4660. IF:7.571
