Dr. Tie Wang, Professor, Researcher, Doctoral supervisor

Vice President of Tianjin University of Technology

Dean of Life and Health Intelligent Research Institute

Director of Tianjin Key Laboratory of Life and Health Detection

Research Interests: Analysis of expiratory gas sensing detection in diseases

E-mail: wangtie@email.tjut.edu.cn

Address: 391 Binshui West Road, Xiqing District, Tianjin, China.

Honors and Awards:

2019, National Natural Science Fund for Distinguished Young Scholars;

2019, National Leading Talents of Science and Technology Innovation in the “Ten Thousand Talents Program”;

2018, Young and Middle-aged Leading Talents in Scientific and Technological Innovation, Ministry of Science and Technology of the People’s Republic of China;

2018, Leader of Innovation Cross Team, Chinese Academy of Sciences;

2014, National Natural Science Fund for Excellent Young Scholars (Final Evaluation);

2013, Youth Project of National Overseas High-level Talents Introduction Program;

2023, Young Innovator Award of Nano Research;

2021, International Association of Advanced Materials Medal;

2018, First Prize of Science and Technology Award of China Association for Instrumental Analysis (Leading Person);

Professional Activities:

Editorial Board Member of Rare Metals

Editorial Board Member of Fundamental Research

Editorial Board Member of Nano Research

Editorial Board Member of Progress in Chemistry

Editorial Board Member of Chemical Journal of Chinese Universities

Main Research Achievements：

Professor Tie Wang has been committed to the fundamental research and clinical application in vitro analysis for detecting diseases based on nanomaterial self-assembled structures and achieved a series of innovative achievements. He has carried out systematic and original studies on key scientific issues surrounding the detection of disease-related biomarkers. Basing on the internal relationship between the mechanical properties of the self-assemblies, regulated micro-nano structure and the disease detection in vitro, a series of novel self-assembled structures of nanomaterials were constructed to detect diseases highly sensitively and selectively in the complex flow system of the physiological environment, exploring the mechanism of the interfacial interaction of the self-assembly micro/nano structures and the chemical information of diseases. The influence factors of different interfacial structures for flow states were also studied to reveal the mechanisms of adsorption dynamics of disease biomarkers. Meanwhile, a series of novel methods and technologies were also developed to detect disease in complex flow system. Further, the portable testing instruments for exhaled breath were developed to break through the rapid detection by the real-time via online analysis for early screening of lung cancer and carry out clinical trials for early detection of diseases, eventually, achieving integrated research platform from fundamental research, instrument development toward clinical testing. He has published more than 110 academic papers in international journals, such asScience,Chem. Soc. Rev.,Adv. Mater.,Angew. Chem.,Nat. Commun.,Sci. Adv.,J. Am. Chem. Soc.and other core journals, and cited by 5800 times. In addition, 20 invention patents have been applied and 12 have been authorized.

Representative Publications：

 1.Xue Lou, Hui Wang, Yu Liu, Yongwei Huang*, Zhonghua Liu, Wei Zhang*, Tie Wang*.Perylene-Based Reactive Oxygen Species Supergenerator for Immunogenic Photochemotherapy against Hypoxic Tumors.Angew. Chem. Int. Ed., 2023, DOI:10.1002/anie.202214586.

2.Xiangyu Chen, Shiyong Teng, Jinming Li, Xuezhi Qiao, Weidong Zhao, Zhengjie Xue, Xudong Shi*, Yuguang Wang*, Wensheng Yang*, Tie Wang*.Gadolinium(III)-Chelated Deformable Mesoporous Organosilica Nanoparticles as Magnetic Resonance Imaging Contrast Agent.Adv. Mater., 2023, 2211578.

3. Xiaobin Huang, Weidong Zhao, Xiangyu Chen, Jinming Li, Haochen Ye, Cancan Li, Xiaomeng Yin, Xinyuan Zhou, Xuezhi Qiao, Zhenjie Xue*, and Tie Wang*.Gold Nanoparticle-Bridge Array to Improve DNA Hybridization Efficiency of SERS Sensors.J.Am. Chem. Soc., 2022,144, 17533-17539.

4. Weidong Zhao, Jinming Li, Zhenjie Xue, Xuezhi Qiao, Ailin Li, Xiangyu Chen, Yun Feng,* Zhou Yang,* Tie Wang*.A Separation-Sensing Platform Performing Accurate Diagnosis of Jaundice in Complex Biological Tear Fluids.Angew. Chem. Int. Ed., 2022, 61, e202205628(1 of 6).

5.Xiao Li*, Zhenjie Xue, Xiangyu Chen, Xuezhi Qiao, Guang Mo, Wensheng Bu, Bo Guan, Tie Wang*.Printable Assemblies of Perovskite Nanocubes on Meter-Scale Panel.Sci. Adv., 2022, DOI: 10.1126/sciadv.add1559.

6. Chuanhui Huang, Xiangyu Chen, Zhenjie Xue, Tie Wang*, Nanoassembled interface for dynamics tailoring,Acc. Chem. Res. 2021, 54, 35-45.

7. Lu Liu, Wei Xiong, Linfeng Cui, Zhenjie Xue, Chuanghui Huang, Qian Song, Wanqiao Bai, Yage Peng, Xiangyu Chen, Keyan Liu, Shuwei Zhang, Lei Wen, Yanke Che,* and Tie Wang.* Universal Strategy for Improving the Sensitivity of Detecting Volatile Organic Compounds by Patterned Arrays.Angew. Chem. Int. Ed., 2020, 59, 15953-15957.

8. Qian Song, Zhenjie Xue, Cong Liu, Xuezhi Qiao, Lu Liu, Chuanhui Hunag, Keyan Liu, Xiao Li, Zhili Lu, and Tie Wang*,General strategy to optimize gas evolution reaction via assembled striped-pattern superlattices,J. Am. Chem. Soc., 2020, 142(4), 1857-1863.

9. Chuanhui Huang, Xiangyu Chen, Zhenjie Xue, Tie Wang*, Effect of structure: A new insight into nanoparticle assemblies from inanimate to animate.Sci. Adv., 2020, 6: eaba1321.

10. Chuanhui Huang, Zhihong Guo, Xu Zheng, Xiangyu Chen, Zhenjie Xue, Shuwei Zhang, Xiao Li, Bo Guan, Xiang Li, Guoqing Hu* and Tie Wang*. Deformable Metal–Organic Framework Nanosheets for Heterogeneous Catalytic Reactions.J. Am. Chem. Soc., 2020, 142(20), 9408-9414.